Ibicuruzwa

1. Inyuguti: Ifu yera cyangwa umuhondo muto, kristaline cyangwa ifu ya amorphous.

2. Gukuramo Inkomoko: Porcine gastric mucosa.

3. Inzira: Pepsin yitandukanije na mucosa yingurube yingurube ikoresheje uburyo budasanzwe bwo kuvoma.

4. Ibyerekana kandi bikoreshwa: Ikoreshwa cyane kuri dyspepsia iterwa no gufata ibiryo bya poroteyine, hypofunction igogora mugihe cyo gukira no kubura proteinase yo mu gifu iterwa na gastrite idakira, kanseri yo mu gifu na anaemia mbi.Pepsin ni enzyme isohoka. muburyo bwigifu bwinyamabere.Ikora kugirango igabanye poroteyine mo peptide ntoya ishobora kwinjizwa n amara mato.

5. Ibikorwa bya Biochem / physiol: Bitandukanye nizindi peptidase nyinshi, pepsin hydrolyzes ihuza peptide gusa, ntabwo ari amide cyangwa ester ihuza.Umwihariko wa clavage urimo peptide hamwe na acide ya aromatic kumpande zombi za peptide, cyane cyane niba ibindi bisigara nabyo ari aromatic cyangwa acide dicarboxylic.Kwiyongera kwanduye hydrolysis bibaho niba hari aside irike irimo aside irike hafi ya peptide, ifite aside amine.Pepsin nayo izahitamo neza kuruhande rwa carboxyl ya fenylalanine na leucine, kandi ku rugero ruto kuruhande rwa carboxyl kuruhande rwa acide glutamic.Ntishobora gukomera kuri valine, alanine, cyangwa glycine.ZL-tyrosyl-L-phenylalanine, ZL-glutamyl-L-tyrosine, cyangwa ZL-methionyl-L-tyrosine irashobora gukoreshwa nka substrate yo gusya pepsin.Pepsine ihagarikwa na peptide nyinshi zirimo fenylalanine.